venofer dosing calculator

Philadelphia, PA: Lippincott Williams & Wilkins;2013;303-307. Iron Sucrose - SlideShare Applies only to oral form of both agents. PDF Protocol for the use of Intravenous Iron Sucrose (Venofer Auerbach M, Witt D, Toler W, Fierstein M, Lerner RG, Ballard H. Clinical use of the total dose intravenous infusion of iron dextran. A target haemoglobin value is also input so iron deficit can be determined according to a specified individual target. Applies only to oral form of both agents. Aranesp (darbepoetin alfa) | Dosing Considerations View the formulary and any restrictions for each plan. Applies only to oral form of both agents. The dosing for iron replacement treatment in pediatric patients with Peritoneal or Hemodialysis-Dependent - CKD or Non-Dialysis Dependent CKD have not been established. For all products, slow initial infusion is prudent; the patient is observed closely for infusion reactions. Patients may present with shock, clinically significant hypotension, loss of consciousness and/or collapse. Administer Venofer only intravenously by slow injection or by infusion. I. You are encouraged to report Adverse Drug Events to American Regent, Inc. at 1-800-734-9236 or to the FDA by visiting www.fda.gov/medwatch or calling 1-800-FDA-1088. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. Each costs about $0.46 to $0.55 per mg of iron. Serious - Use Alternative (1)iron sucrose decreases levels of tetracycline by inhibition of GI absorption. feasible, Maximum total cumulative iron sucrose dose administered in 14 days is 1000 mg elemental iron. Applies only to oral form of both agents. Deferiprone may bind polyvalent cations (eg, iron, aluminum, and zinc), separate administration by at least 4 hr between deferiprone and other medications (eg, antacids), or supplements containing these polyvalent cations. FERAHEME Dosing & Administration - Feraheme FOR PATIENTS WEIGHING 50 kg OR MORE: Administer 1000 mg of Monoferric by intravenous infusion 20 minutes as a single dose 1. https://www.uptodate.com/ (Requires subscription). Hemodialysis-dependent CKD: 100 mg elemental iron IV (injection or infusion over 2-5 min) per dialysis session not to exceed total cumulative dose of 1000 mg divided in 3 doses/week. Maximum recommended single dose: 300 mg (See Prescriber's Orders). Avoid or Use Alternate Drug. Kidney Int. Serious - Use Alternative (1)iron sucrose decreases levels of demeclocycline by inhibition of GI absorption. Iron Sucrose Monograph for Professionals - Drugs.com All Rights Reserved. Applies only to oral form of both agents. 2 DOSAGE & ADMINISTRATION Venofer must only be administered intravenously either by slow injection or by infusion. For iron maintenance treatment, administer Venofer, (2 years of age or older) with NDD-CKD or PDD-CKD who are on erythropoietin therapy for iron maintenance treatment. Pregnancy: Risk Summary-Clinical Considerations. Minor/Significance Unknown. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022. 1988 May;111(5):566-70. Minor/Significance Unknown. official version of the modified score here. In this study and another study evaluating a single intravenous dose of iron sucrose containing 500-700 mg of iron in 26 anemic patients on erythropoietin therapy (23 female, 3 male; age range 16-60), approximately 5% of the iron was . Venofer treatment may be repeated if iron deficiency reoccurs. Iron Sucrose Protocol - Cmqcc Venofer is manufactured under license from Vifor (International) Inc., Switzerland. Applies only to oral form of both agents. Situation Analysis Market Size MAT Sales Cr LC MAT Share % MAT Gr % Total Pharma Market 9388.69 100 13.5 Iron Sucrose 11.18 93.81 37.65 Brand Company Saline MAT . Data from Ferrlecit postmarketing spontaneous reports indicate that individual doses exceeding 125 mg may be associated with a higher incidence and/or severity of adverse events. Applies only to oral form of both agents. You can further save the PDF or print it. Separate by 2 hr. Venofer (iron sucrose) dose calculator | Calculosaurus.com Clinical calculators for obstetrics and gynaecology VTE risk assessment Calculator menu Venofer dose calculator Iron sucrose Not what you were looking for? Applies only to oral form of both agents. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. PDF Iron Sucrose: Guidelines for Administration Document Type: Guideline Untreated IDA in pregnancy is associated with adverse maternal outcomes such as post-partum anemia. Applies only to oral form of both agents. Ganzoni AM. Although anaphylactic reactions known to occur following INFeD administration are usually evident within a few minutes, or sooner, it is recommended that a period of an hour or longer elapse before the remainder of the initial therapeutic dose is given. Patients with a history of drug allergy or multiple drug allergies may be at increased risk of anaphylactic-type reactions to INFeD. Applies only to oral form of both agents. These can be input in g/dL, g/L or mmol/L. Avoid or Use Alternate Drug. iron sucrose decreases levels of mycophenolate by inhibition of GI absorption. aluminum hydroxide will decrease the level or effect of iron sucrose by increasing gastric pH. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: vitamin products, other iron-containing products. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. This iron deficiency calculator determines the iron deficit based on patient weight, hemoglobin and iron stores to prepare for iron replacement. DOSAGE AND ADMINISTRATION: The recommended dose of Feraheme is an initial 510 mg dose followed by a second 510 mg dose 3 to 8 days later. HOW TO USE: This medication is given by injection into a vein as directed by your doctor. Pain, swelling, or redness at the injection site may occur. The therapeutic management of IDA focuses on the replenishment of the iron stores through methods that have been mentioned above. Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator, Red Blood Cell (RBC) Indices Calculator, Iron Deficiency In Pregnancy Calculator. Calculation of Iron Deficit - Perinatology.com Avoid or Use Alternate Drug. Interaction only with oral iron administration. deferoxamine decreases levels of iron sucrose by inhibition of GI absorption. https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvdmVub2Zlci1pcm9uLXN1Y3Jvc2UtMzQyMTYy, View explanations for tiers and The recommendation is that most adults need a cumulative dose of elemental iron of at least 1 g. Iron replenishment can be done intravenously, either as total dose (example: iron-dextran or iron carboxymaltose) or as split dose (example: iron sucrose). Minor/Significance Unknown. Avoid or Use Alternate Drug. Venofer / Products / American Regent Our dosage calculator can help you with this as well. In: Koda-Kimble & Young's Applied Therapeutics: The Clinical Use of Drugs. Copyright 1993-2021 Next Steps Evidence Creator Insights Dr. Andreas M. Ganzoni About the Creator Intravenous iron therapy for patients with anemia vitamin E decreases levels of iron sucrose by increasing hepatic clearance. Applies only to oral form of both agents. Use Caution/Monitor. Minor/Significance Unknown.iron sucrose increases levels of calcium acetate by enhancing GI absorption. Venofer Injection Prescribing Information - Drugs.com Individual doses of 2 mL or less may be given on a daily basis until the calculated total amount required has been reached. Separate dosing of tetracyclines from these products. Symptoms associated with Venofer total dosage or infusing too rapidly included hypotension, dyspnea, headache, vomiting, nausea, dizziness, joint aches, paresthesia, abdominal and muscle pain, edema and cardiovascular collapse. Parenteral iron dextran therapy. After total replacement dose completed, need for ongoing IV doses should be re-assessed monthly. Venofer has not been studied in patients younger than 2 years old. Hollands J, Foote E, Rodriguez A. Applies only to oral form of both agents. Discuss the risks and benefits with your doctor.This medication passes into breast milk. Administer Venofer early during the dialysis session (generally within the first hour). Use Caution/Monitor. 2. iron sucrose increases levels of calcium gluconate by enhancing GI absorption. Am J Kid Dis 2001; 38 988991. Applies only to oral form of both agents. Safety of highdose iron sucrose infusion in hospitalized patients with chronic kidney disease. Dosage: For patients weighing 50 kg (110 lb) or more: Give Injectafer in two doses separated by at least 7 days. Studies in monkeys showed concurrent use with calcium, aluminum, or iron caused significantly decreased plasma levels. Crown Rump Length and Nuchal Translucency. Med J Aust. iron sucrose, benazepril. Schweiz Med Wochenschr; 100(7):301-3. sodium citrate/citric acid will decrease the level or effect of iron sucrose by increasing gastric pH. Intravenous iron sucrose: establishing a safe dose. This information does not assure that this product is safe, effective, or appropriate for you. For adult CKD patients on ESA therapy who are not receiving iron supplementation, the guideline suggests a trial of IV iron (or in NDD-CKD patients, alternatively, a 1- to 3-month trial of oral iron therapy) if: CKD=chronic kidney disease ESA=erythropoietin-stimulating agent Hb=hemoglobin IV=intravenous RBC=red blood cell WBC=white blood cell. Your doctor will do laboratory tests to monitor your response. Taking the case of a patient weighing 75 kg (165.3 lbs) with a target hemoglobin value of 13 g/dL (130 g/L or 8.07 mmol/L), an actual hemoglobin of 9.5 g/dL (95 g/L or 5.9 mmol/L) and iron stores of 500 mg, the iron deficit is: Iron deficit = 75 x (13 9.5) x 2.4 + 500 = 1,130 mg. Administer ciprofloxacin at least 2 hours before or 6 hours after using these products. Ferric carboxymaltose (Ferinject) for iron-deficiency anaemia Applies only to oral form of both agents. The dosing for iron replacement treatment in pediatric patients with hemodialysis-dependent chronic kidney disease (HDD-CKD), non-dialysis-dependent chronic kidney disease (NDD-CKD) or peritoneal-dialysis-dependent chronic kidney disease (PDD-CKD) has not been established. Minor/Significance Unknown. Monitor Closely (1)aluminum hydroxide will decrease the level or effect of iron sucrose by increasing gastric pH. Applies only to oral form of both agents. Monitor Closely (1)deferoxamine decreases levels of iron sucrose by inhibition of GI absorption. Minor/Significance Unknown. FERAHEME was non-inferior to Venofer (iron sucrose) in mean Hgb rise from baseline 2,5. When administering as a slow intravenous push, give at the rate of approximately 100 mg (2 mL) per minute. Initial infusion rate. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin, Do not mix with other medications or add to parenteral nutrition solutions for IV infusion, Do not dilute to concentrations below 1 mg/mL, Add dose to 0.9% NaCl infusion bags (PVC or non-PVC); final concentrations range is 1-2 mg of elemental iron/mL, Visually inspect for particulate matter and discoloration prior to infusion, Stable for 7 days at controlled room temperature (25C). Interaction only with oral iron administration. Applies only to oral form of both agents. Separate dosing of tetracyclines from these products. Talk to your pharmacist for more details.During pregnancy, this medication should be used only when clearly needed. Adults and Children over 15 kg (33 lbs): Dose (mL) = 0.0442 (Desired Hb - Observed Hb) x LBW + (0.26 x LBW), Desired Hb = the target Hb in g/dl. Diagnosis and management of iron deficiency anaemia: a clinical update. Copyright 1993-2021 ONE DOSE. Multivalent cation-containing products may impair absorption of tetracyclines, which may decrease its efficacy. iron sucrose decreases levels of ofloxacin by inhibition of GI absorption. Modify Therapy/Monitor Closely. DOSAGE AND ADMINISTRATION: Oral iron should be discontinued prior to administration of INFeD. Applies only to oral form of both agents. We comply with the HONcode standard for trustworthy health information. Have resuscitation equipment and personnel trained in the detection and treatment of anaphylactic-type reactions readily available during INFeD administration. On the other hand, slow decreases, such as that in chronic occult gastrointestinal bleeding are often difficult to diagnose. These adverse reactions have occurred up to 30 minutes after the administration of Venofer injection. For additional Safety Information, please see Full Prescribing Information. Minor/Significance Unknown.iron sucrose increases levels of calcium citrate by enhancing GI absorption. 1. Iron Injection Administration | INJECTAFER HCP Avoid or Use Alternate Drug. This drug is available at a middle level co-pay. Applies only to oral form of both agents. The dose of Venofer must be individually calculated for each patient according to the total iron deficit calculated with the following Ganzoni formula, for example: Total iron deficit [mg] = BW [kg] x (target Hb - actual Hb) [g/dl] x 2.4* + storage iron [mg] Below 35 kg BW: 35 kg BW and above: Target Hb = 13 g/dl and storage iron = 15 mg/kg BW Serious - Use Alternative (1)iron sucrose decreases levels of mycophenolate by inhibition of GI absorption. Monitor Closely (1)iron sucrose decreases levels of penicillamine by inhibition of GI absorption. Monitor Closely (1)iron sucrose decreases levels of liothyronine by inhibition of GI absorption. Monitor Closely (1)vitamin E decreases levels of iron sucrose by increasing hepatic clearance. Hemoglobin can be input in g/dL, g/L or mmol/L and refers to the amount of hemoglobin in the red blood cells. Monitor Closely (1)pantoprazole will decrease the level or effect of iron sucrose by increasing gastric pH. Only administer Feraheme as an intravenous infusion over at least 15 minutes and only when personnel and therapies are immediately available for the treatment of anaphylaxis and other hypersensitivity reactions. Administer iron products at least 2 hr before and no less than 6 hr after each dose to avoid chelation with magnesium. Use Caution/Monitor. If hypersensitivity reactions or signs of intolerance occur during administration, stop Venofer immediately. Applies only to oral form of both agents. IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. Minor (2)calcium citrate decreases levels of iron sucrose by inhibition of GI absorption. Separate by at least 4 hours. 2015: 763576. ANNA J. Before using, check this product visually for particles or discoloration. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Clinical calculators for obstetrics and gynaecology - calculosaurus Minor/Significance Unknown.iron sucrose increases levels of calcium gluconate by enhancing GI absorption. Serious - Use Alternative (1)iron sucrose decreases levels of gemifloxacin by inhibition of GI absorption. Treatment of anemia due to iron deficiency. 300-500 mg Iron Sucrose in NS 250 mL administered over three (3) hours; may repeat as needed in 3-7 days to reach 1 gm. Applies only to oral form of both agents. Iron Deficiency in Heart Failure - Home - American College of Cardiology Administer Venofer 100 mg undiluted as a slow intravenous injection over 2 to 5 minutes, or as an infusion of 100 mg diluted in a maximum of 100 mL of 0.9% NaCl over a period of at least 15 minutes, per consecutive hemodialysis session [see How Supplied/Storage and Handling (16.2).] Applies only to oral form of both agents. Anemia; 2015: 763576. Burns DL, Mascioli EA, Bistrian BR. MISSED DOSE: It is important to get each dose of this medication as scheduled. 1974 Jun;31(6):592-5. Hemoglobin iron deficit = 60 x (14 - 8) x (2.145) = 772 mg iron. Initial symptoms may include hypotension, syncope, unresponsiveness, cardiac/cardiorespiratory arrest. We have found the lower dose to be better tolerated in the second half of gestation. During all INFeD administrations, observe for signs or symptoms of anaphylactic-type reactions. iron sucrose decreases levels of thyroid desiccated by inhibition of GI absorption. Most reactions associated with intravenous iron preparations occur within 30 minutes of the completion of the infusion. Intermediate calculations: -Blood volume (dL) = [65 (mL/kg) x body weight (kg)] / 100 (mL/dL) -Hgb deficit (g/dL) = 14.0 - patient hgb conc. Corrected Sodium and Effective Osmolality. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. MDCalc loves calculator creators researchers who, through intelligent and often complex methods, discover tools that describe scientific facts that can then be applied in practice. 0.5 mg/kg (not to exceed 100 mg/dose) diluted to a concentration of 1 to 2 mg/mL in 0.9% sodium chloride IV over 5 to 60 minutes Administer every 4 weeks for 12 weeks Do not dilute to concentrations below 1 mg/mL Comments: Treatment may be repeated if necessary. Your list will be saved and can be edited at any time. Can't find what you need? Minor/Significance Unknown. Applies only to oral form of both agents. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Consult your pharmacist or local waste disposal company. Applies only to oral form of both agents. Immune system disorders: Anaphylactic-type reactions, angioedema, Nervous system disorders: Convulsions, collapse, light-headedness, loss-of-consciousness, Respiratory, thoracic and mediastinal disorders: Bronchospasm, dyspnea, Musculoskeletal and connective tissue disorders: Back pain, swelling of the joints, General disorders and administration site conditions: Hyperhidrosis, Published studies on intravenous iron sucrose treatment after first trimester of pregnancy not shown adverse maternal or fetal outcomes; available reports of intravenous iron sucrose use in pregnant women during first trimester are insufficient to assess risk of major birth defects and miscarriage; iron deficiency anemia during pregnancy should be treated because there are risks to mother and fetus associated with untreated iron deficiency anemia (IDA) in pregnancy; risks to fetus associated with maternal severe hypersensitivity reactions, Severe adverse reactions including circulatory failure (severe hypotension, shock including in the context of anaphylactic reaction) may occur in pregnant women with parenteral iron products which may cause fetal bradycardia, especially during second and third trimester, Iron sucrose is present in human milk, and available published reports following exposure to 100-300 mg intravenous iron sucrose have not reported adverse reactions in breastfed infants; there are no data on effects on milk production, Developmental and health benefits of breastfeeding should be considered, along with mothers clinical need for treatment and any potential adverse effects on breastfed child from therapy or from underlying maternal condition. There are three fields in the parenteral iron replacement for iron deficiency anemia calculator: Weight can be input in either lbs or kilograms and the required transformations are performed by the calculator. Use Caution/Monitor. Avoid or Use Alternate Drug. Applies only to oral form of both agents. Med J Aust; 193(9):525-32. Administer on 5 different occasions over a 14 day period. Applies only to oral form of both agents. Read our. Applies only to oral form of both agents. May increase risk of hypotension. Do not administer Venofer to patients with evidence of iron overload. Do Not Copy, Distribute or otherwise Disseminate without express permission. commonly, these are "preferred" (on formulary) brand drugs. The dosing for iron replacement treatment in pediatric patients with NDD-CKD or PDDCKD has not - been established. Steps on how to print your input & results: 1. Applies only to oral form of both agents. The factor 2.4 comes about from the calculation that the total iron content of hemoglobin is 0.34%, the blood volume accounts for 7% . Venofer Injection Dosage Guide - Drugs.com Serious - Use Alternative (1)iron sucrose decreases levels of fleroxacin by inhibition of GI absorption. Anemia of chronic disease (ACD), Calculation of the Total Iron Deficit equation appears in Cosmofer PI, Calculation of the Total Iron Deficit Alternative equation, Iron Dextran Dosing Calculator (iron deficit), HONcode standard for trust- worthy health, Pediatric Oncology: Diagnosis And Prognosis Communication, Pharmacosmos A/S, CosmoFer low molecular weight (Mw) iron dextran. The above information is provided for general Official Journal of the International Society of Nephrology. Uses for Iron Sucrose Iron Deficiency In Pregnancy Calculator, Mean Corpuscular Hemoglobin Concentration (MCHC) Calculator. Privacy Policy, Use 500 mg for adults and children 35 kg; use 15 mg/kg if <35 kg. If dose exceeds 20mg/kg it should be rounded down to 20mg/kg OR administration of the total dose has to be split and given 7 days apart. Prescribing and dispensing information For iron sucrose A complex of ferric hydroxide with sucrose containing 2% (20 mg/mL) of iron. Each mL contains 20 mg of elemental iron. Observed Hb = the patients current hemoglobin in g/dl. Information last revised December 2022. Applies only to oral form of both agents. PDF IRON PRODUCT CHOICE AND DOSE CALCULATION - Blood Applies only to oral form of both agents. Schrier SL, Mentzer WC, Landaw SA. 1998 Feb;25(1):65-8. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Venofer (iron sucrose) Uses, Dosage, Side Effects - Drugs.com 1982;13(4):309-21. VenAccess is a trademark of Vifor (International) Inc. Switzerland. Monitor Closely (1)deferasirox decreases levels of iron sucrose by inhibition of GI absorption. Contraindicated. This may be helped by giving the medication more slowly or at a lower dose. 4) Gozzard D. (2011) When is high-dose intravenous iron repletion needed? omeprazole will decrease the level or effect of iron sucrose by increasing gastric pH. FERAHEME met the predefined criteria for non-inferiority to Venofer . Allow at least 30 minutes between administration of Feraheme and administration of other medications that could potentially cause serious hypersensitivity reactions and/or hypotension, such as chemotherapeutic agents or monoclonal antibodies. This website is intended for use by US healthcare professionals only. Feraheme, when added to intravenous infusion bags containing either 0.9% Sodium Chloride Injection, USP (normal saline), or 5% Dextrose Injection, USP, at concentrations of 2-8 mg elemental iron per mL, should be used immediately but may be stored at controlled room temperature (25C 2C) for up to 4 hours or refrigerated (2-8 C) for up to 48 hours. Use Caution/Monitor. Applies only to oral form of both agents. Applies only to oral form of both agents. iron sucrose decreases levels of minocycline by inhibition of GI absorption. For iron maintenance treatment: Administer Venofer at a dose of 0.5 mg/kg, not to exceed 100 mg per dose, every four weeks for 12 weeks given undiluted by slow intravenous injection over 5 minutes or

H E B Weekly Ad Beaumont Tx, Food Challenges Westchester Ny, Small Hall Hire London, How To Turn Off Night Mode On Android Camera, Articles V